• Product NamePRAME Antibody FITC Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsFlow-Cyt ICC IF
• Species ReactivityHu Ms
• Immunogen DescriptionKLH conjugated synthetic peptide aa 180-227 509 derived from human PRAME
• ConjugatesFITC
• Excitation Emission494nm 518nm
• Target NamePRAME
• Alternative Names    MAPE; OIP4; CT130; OIP-4; Melanoma antigen preferentially expressed in tumors; Opa-interacting protein 4; Preferentially expressed antigen of melanoma; PRAME
• Accession No. Swiss-Prot#P78395
  NCBI Gene ID23532
• UniprotP78395
• Gene ID23532;
• Cell Localization Nucleus, Cell membrane
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200

Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting