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PHB(Phospho-Thr258) Antibody #11588

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Datasheet PDF
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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NamePHB(Phospho-Thr258) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of PHB only when phosphorylated at threonine 258.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of threonine 258 (N-I-T(p)-Y-L) derived from Human PHB.
  • Target NamePHB
  • ModificationPhospho
  • Alternative Names    Prohibitin; PHB1
  • Accession No. Swiss-Prot: P35232;
    NCBI Gene ID: 5245;
    NCBI Protein: NP_001268425.1.
  • UniprotP35232
  • Gene ID5245;
  • SDS-PAGE MW 29
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C
Application Details
Background

Published Papers

A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3PBX1 and β-cateninABCG2 signaling.In J Biomed Sci. On 2020 Mar 13; by Fang CH, Lin YT, et al..PMID: 32169072 , , (2020),
PMID: 32169072
Olfactory Bulb Neuroproteomics Reveals a Chronological Perturbation of Survival Routes and a Disruption of Prohibitin Complex During Alzheimer's Disease Progression.Sci Rep on 2017 Aug 22 by Mercedes Lachn-Montes, Andrea Gonzlez-Morales,et al..PMID: 28831118, , (2017),
PMID: 28831118
Please let us know if you have published research using #11588 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep