• Product NameDDX58 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC,IF
• Species ReactivityHuman,Mouse
• SpecificityThe antibody detects endogenous level of total DDX58 protein.
• Immunogen TypePeptide
• Immunogen DescriptionA synthetic peptide of human RIG-I / DDX58 (NP_055129.2).
• Target NameDDX58
• Alternative Names    DDX58;RIG-I;RIGI;RLR-1;SGMRT2
• Accession No. Uniprot:O95786
  GeneID:23586
• UniprotO95786
• Gene ID23586
• SDS-PAGE MW 109kDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200
  IF 1:20 - 1:100

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.

• Western blot analysis of extracts of various cell lines, using RIG-I / DDX58 antibody.
• Immunohistochemistry of paraffin-embedded human prostate using RIG-I / DDX58 antibody.
• Immunofluorescence analysis of L929 cells using RIG-I / DDX58 Rabbit pAb.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting