• Product NameFGF Receptor 1(Ab-154) Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous level of total FGF Receptor 1 protein.
• Immunogen TypePeptide-KLH
• Immunogen DescriptionPeptide sequence around aa.152~156 (A-P-Y-W-T) derived from Human FGF Receptor 1.
• Target NameFGF Receptor 1
• Alternative Names    FGFBR; FGFR-1; FGR1; FLG; FLT2
• Accession No. Swiss-Prot: P08581
  NCBI Protein: NP_001167534.1
• UniprotP08581
• Gene ID4233;
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

• Predicted MW: 145kd
  Western blotting: 1:500~1:1000
  

FGF encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.

Wu X,et al.(2001)Acta Obstet Gynecol Scand.80(6):497-504.
Faraone D,et al.(2006) Blood. 107(5):1896-902.
Claus P,et al.(2004)Neurosci Lett.360(3):117-20.

• Western blot analysis of extracts from 3T3 cells using FGF Receptor 1(Ab-154) Antibody #21231 and the same antibody preincubated with blocking peptide.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting