• Product NameA2M Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total A2M protein.
• Immunogen TypePeptide
• Immunogen DescriptionRecombinant fusion protein of human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M)) (NP_000005.2).
• Target NameA2M
• Alternative Names    A2M;A2MD;CPAMD5;FWP007;S863-7
• Accession No. Uniprot:P01023
  GeneID:2
• UniprotP01023
• Gene ID2
• SDS-PAGE MW 160kDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.

• Western blot analysis of extracts of various cell lines, using Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M)) antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting