• Product NameKCNN4 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB
• Species ReactivityHuman
• SpecificityThe antibody detects endogenous level of total KCNN4 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human KCNN4.
• Target NameKCNN4
• Alternative Names    IK1; SK4; KCA4; hSK4; IKCA1
• Accession No. Swiss-Prot:O15554
  NCBI Gene ID:3783
• UniprotO15554
• Gene ID3783;
• SDS-PAGE MW 47KD
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.

• Western blot analysis of extracts of HepG2 cells, using KCNN4 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting