• Product NameADRBK2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total ADRBK2 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human ADRBK2.
• Target NameADRBK2
• Alternative Names    GRK3; BARK2;
• Accession No. Swiss-Prot:P35626
  NCBI Gene ID:157
• UniprotP35626
• Gene ID157;
• SDS-PAGE MW 80KD
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

• Western blot analysis of extracts of various cell lines, using ADRBK2 at 1:1000 dilution.
• Immunohistochemistry of paraffin-embedded rat spinal cord using ADRBK2 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded mouse brain using ADRBK2 at dilution of 1:100 (40x lens).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting