• Product NameCDKN3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB,IHC,IF
• Species ReactivityHuman,Mouse
• SpecificityThe antibody detects endogenous level of total CDKN3 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human CDKN3.
• Target NameCDKN3
• Alternative Names    CDI1; CIP2; FLJ25787; KAP; KAP1
• Accession No. Swiss-Prot:Q16667
  NCBI Gene ID:1033
• UniprotQ16667
• Gene ID1033;
• SDS-PAGE MW 24KD
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200
  IF 1:50 - 1:200

The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Western blot analysis of extracts of mouse liver, using CDKN3 at 1:1000 dilution.
• Immunofluorescence analysis of MCF-7 cells using CDKN3 . Blue: DAPI for nuclear staining.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting