• Product NameDIABLO Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total DIABLO protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant fusion protein of human Smac/Smac/Diablo (NP_063940.1).
• Target NameDIABLO
• Alternative Names    DIABLO;DFNA64;SMAC
• Accession No. Uniprot:Q9NR28
  GeneID:56616
• UniprotQ9NR28
• Gene ID56616
• SDS-PAGE MW 18kDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Immunohistochemistry of paraffin-embedded rat testis using Smac/Diablo Rabbit pAb.
• Western blot analysis of extracts of various cell lines, using Smac/Diablo antibody.
• Immunohistochemistry of paraffin-embedded mouse testis using Smac/Diablo Rabbit pAb.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting