• Product NameWNK1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB,IF
• Species ReactivityHuman
• SpecificityThe antibody detects endogenous level of total WNK1 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human WNK1.
• Target NameWNK1
• Alternative Names    KDP; PSK; p65; HSN2; HSAN2
• Accession No. Swiss-Prot:Q9H4A3
  NCBI Gene ID:65125
• UniprotQ9H4A3
• Gene ID65125;
• SDS-PAGE MW 250KD
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IF 1:50 - 1:200

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.

• Immunofluorescence analysis of HeLa cells using WNK1 . Blue: DAPI for nuclear staining.
• Western blot analysis of extracts of various cell lines, using WNK1 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting