• Product NameGRB2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IF
• Species ReactivityHuman,Mouse
• SpecificityThe antibody detects endogenous level of total GRB2 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant fusion protein of human GRB2 (NP_002077.1).
• Target NameGRB2
• Alternative Names    ASH;EGFRBP-GRB2;Grb3-3;MST084;MSTP084;NCKAP2;GRB2
• Accession No. Uniprot:P62993
  GeneID:2885
• UniprotP62993
• Gene ID2885
• SDS-PAGE MW 33kDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IF 1:10 - 1:100

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Immunofluorescence analysis of HeLa cells using GRB2 antibody.
• Western blot analysis of extracts of various cell lines, using GRB2 antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting