• Product NameSOX2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous level of total SOX2 protein.
• Immunogen TypePeptide-KLH
• Immunogen DescriptionPeptide sequence around aa.76~80 (G-A-E-W-K) derived from SOX2
• Target NameSOX2
• Alternative Names    Transcription factor SOX-2
• Accession No. Swiss-Prot: P48431
  NCBI Protein: NP_003097.1
• UniprotP48431
• Gene ID6657;
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

• Predicted MW: 35kd
  Western blotting: 1:1000
  

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency

Yuan H, et al. Genes Dev. 1995 Nov 1;9(21):2635-45
Muta M, et al. Genes Cells 2002 Aug;7(8):791-805
Tomioka M, et al. Nucleic Acids Res. 2002 Jul 15; 30(14): 3202-3213.

• Western blot analysis of extracts from human Umbilical cord mesenchymal stem cell using SOX2 Antibody #21425.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting