• Product NameCD2L1Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total CD2L1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from N-terminal of human CD2L1.
• Target NameCD2L1
• Alternative Names    CD2L1; CDC2L1; CDK11; CLK-1; Cell division cycle 2-like 1
• Accession No. Swiss-Prot: P21127
  NCBI Gene ID: 984
• UniprotP21127
• Gene ID984;
• SDS-PAGE MW 92kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform mayact as a negative regulator of normal cell cycle progression.

Bunnell B.A., Proc. Natl. Acad. Sci. U.S.A. 87:7467-7471(1990).
Eipers P.G., Genomics 13:613-621(1992).
Xiang J., J. Biol. Chem. 269:15786-15794(1994).

• Western blot analysis of extracts from HepG2 cells and HUVEC cells, using CD2L1 antibody #33712.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting