• Product NameT4S1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsIHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total T4S1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human T4S1.
• Target NameT4S1
• Alternative Names    Transmembrane 4 L6 family member 1; Tumor-associated antigen L6; Membrane component surface marker 1; M3S1; TM4SF1
• Accession No. Swiss-Prot: P30408
  NCBI Gene ID: 4071
• UniprotP30408
• Gene ID4071;
• SDS-PAGE MW 22kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:50~1:100
  

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas.

Marken J.S., Proc. Natl. Acad. Sci. U.S.A. 89:3503-3507(1992).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Marken J.S., J. Biol. Chem. 269:7397-7401(1994).

• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using T4S1 antibody #33745.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting