• Product NameZFHX3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsIHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total ZFHX3 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human ZFHX3.
• Target NameZFHX3
• Alternative Names    Zinc finger homeodomain protein 3; ZFH-3; Alpha-fetoprotein enhancer-binding protein; AT motif-binding factor; AT-binding transcription factor 1
• Accession No. Swiss-Prot: Q15911
  NCBI Gene ID: 463
• UniprotQ15911
• Gene ID463;
• SDS-PAGE MW 405kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:50~1:100
  

Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer.

Miura Y., J. Biol. Chem. 270:26840-26848(1995).
Morinaga T., Mol. Cell. Biol. 11:6041-6049(1991).
Martin J., Nature 432:988-994(2004).

• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ZFHX3 antibody #33910.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting