• Product NameSTRAD Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IF/ICC,ELISA(peptide)
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total STRAD protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human STRAD.
• Target NameSTRAD
• Alternative Names    STE20-related adapter protein; STRAD alpha; Serologically defined breast cancer antigen NY-BR-96; STRAD; LYK5
• Accession No. Swiss-Prot: Q7RTN6
  NCBI Gene ID: 92335
• UniprotQ7RTN6
• Gene ID92335;
• SDS-PAGE MW 46kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  IF/ICC 1:100-1:500
  ELISA(peptide) 1:20000-1:40000

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Scanlan M.J., Cancer Immun. 1:4-4(2001).
Ota T., Nat. Genet. 36:40-45(2004).
Baas A.F., EMBO J. 22:3062-3072(2003).

• Western blot analysis of extracts from HepG2 cells, using STRAD antibody #33947.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting