• Product NameDCLK2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total DCLK2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human DCLK2.
• Target NameDCLK2
• Alternative Names    Serine/threonine-protein kinase DCLK2; EC 2.7.11.1; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2; DCLK2
• Accession No. Swiss-Prot: Q8N568
  NCBI Gene ID: 166614
• UniprotQ8N568
• Gene ID166614;
• SDS-PAGE MW 83kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm By similarity.

Totoki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 434:724-731(2005).
The German cDNA consortium, Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.

• Western blot analysis of extracts from HepG2 cells, using DCLK2 antibody #33967.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting