• Product NameANKK1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ANKK1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human ANKK1.
• Target NameANKK1
• Alternative Names    Ankyrin repeat and protein kinase domain-containing protein 1; EC 2.7.11.1; Protein kinase PKK2; X-kinase; Sugen kinase 288
• Accession No. Swiss-Prot: Q8NFD2
  NCBI Gene ID: 255239
• UniprotQ8NFD2
• Gene ID255239;
• SDS-PAGE MW 84kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.

Neville M.J., Hum. Mutat. 23:540-545(2004).
Dubertret C., Schizophr. Res. 67:75-85(2004).
Manning G., Science 298:1912-1934(2002).

• Western blot analysis of extracts from HeLa cells, using ANKK1 antibody #33977.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting