• Product NameGBP1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IF
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total GBP1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human GBP1.
• Target NameGBP1
• Alternative Names    GBP-1; Guanine nucleotide-binding protein 1; Interferon-gamma inducible protein MAG-1; Interferon-induced guanylate-binding protein 1; MAG-1
• Accession No. Swiss-Prot: P32455
  NCBI Gene ID: 2633
• UniprotP32455
• Gene ID2633;
• SDS-PAGE MW 68kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  Immunofluorescence: 1:100~1:500

Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.

Cheng Y.-S.E., Mol. Cell. Biol. 11:4717-4725(1991).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Nantais D.E., J. Leukoc. Biol. 60:423-431(1996).

• Western blot analysis of extracts from HUVEC cells, using GBP1 antibody #34250.
• Immunofluorescence analysis of MCF-7 cells, using GBP1 antibody #34250.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting