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GAPDH Antibody #21612

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
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Description
  • Product NameGAPDH Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • ApplicationsWB
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of total GAPDH protein.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around aa.252~256(P-A-K-Y-D) derived from Human GAPDH.
  • Target NameGAPDH
  • Alternative Names    G3PD; GAPD; MGC88685
  • Accession No. Swiss-Prot: P04406
    NCBI Protein: NP_002037.2
  • UniprotP04406
  • Gene ID2597;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Methyl vanillate for inhibiting the proliferation, migration, and epithelial-mesenchymal transition of ovarian cancer cells via the ZEB2/Snail signaling pathwayInTransl Cancer ResOn?2023 Apr 28byLing Wang?#?1,?Yali Miao et al..PMID:?37180664, , (2023),
PMID: 37180664
S-nitrosylation of EMMPRIN influences the migration of HSCs and MMP activity in liver fibrosisInActa Biochim Biophys SinOn2023 Sep 12byXinyan Zhu?1,?Zihui Tang et al..PMID:?37700592, , (2023),
PMID: 37700592
Curved Nanofiber Network Induces Cellular Bridge Formation to Promote Stem Cell MechanotransductionInAdv Sci (Weinh)On2023 JanbyQian Sun?1?2,?Fang Pei et al..PMID:?36382560, , (2023),
PMID: 36382560
High-fat diet causes mitochondrial damage and downregulation of mitofusin-2 and optic atrophy-1 in multiple organsInJ Clin Biochem NutrOn2023 JulbyPeng Zheng?1,?Wenjing Ma et al..PMID:?37534099, , (2023),
PMID: 37534099
View All Published Papers METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2—breast cancerBreast Cancer Res2023 Feb 10Dengjie Ouyang, Tao Hong et al..PMID:36765397, , (2023),
PMID: 36765397
Iridium nanozyme-mediated photoacoustic imaging-guided NIR-II photothermal therapy and tumor microenvironment regulation for targeted eradication of cancer stem cellsInActa BiomaterOn2023 DecbyYuying Yao , Zhuangzhuang Zhao et al..PMID:37852456, , (2023),
PMID: 37852456
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancementIn Eur J PharmacolOn2023 Nov 15byPeng Zheng , Qian Zhang et al..PMID:37806539, , (2023),
PMID: 37806539
Treponema denticola Induces Neuronal Apoptosis by Promoting Amyloid-β Accumulation in Mice. In Pathogens on 2022 Oct 5 by Linrui Wu, Xinyi Su, et al..PMID: 36297207, , (2022),
PMID: 36297207
Double-Edged Sword Effect of Pyroptosis: The Role of Caspase-1/-4/-5/-11 in Different Levels of Apical Periodontitis. In Biomolecules on 2022 Nov 8 by Zhiwu Wu, Mingming Li,et al..PMID:36359010, , (2022),
PMID: 36359010
Penetrating Macrophage-Based Nanoformulation for Periodontitis Treatment. In ACS Nano on 2022 Nov 22 by Na Yan, Junchao Xu, et al..PMID:36288552, , (2022),
PMID: 36288552
Expression of functional thyroid-stimulating hormone receptor in microgliaExpression du r��cepteur fonctionnel de l��hormone thyr��ostimulante dans la microglie, , (2022),
PMID: #N/A
Period 2 Suppresses the Malignant Cellular Behaviors of Colorectal Cancer Through the Epithelial-Mesenchymal Transformation Process. In Cancer Control on 2022 Jan-Dec by Yubo Xiong, Yifan Zhuang,et al..PMID:35220799, , (2022),
PMID: 35220799
Endothelial Transient Receptor Potential Canonical Channel Regulates Angiogenesis and Promotes Recovery After Myocardial Infarction. In J Am Heart Assoc on 2022 Mar 15 by Xin Wen, Yidi Peng, et al..PMID:35253458, , (2022),
PMID: 35253458
Curved Nanofiber Network Induces Cellular Bridge Formation to Promote Stem Cell Mechanotransduction. In Adv Sci (Weinh) on 2023 Jan by Qian Sun, Fang Pei, et al..PMID:36382560, , (2022),
PMID: 36382560
Effects of α-Lipoic Acid on Phagocytosis of Oligomeric Beta-Amyloid1�C42 in BV-2 Mouse Microglial Cells. In Front Aging Neurosci on 2022 Jan 12 by Chih-Yuan Ko, Jian-Hua Xu, et al..PMID: 35095473, , (2022),
PMID: 35095473
Delayed neutrophil apoptosis may enhance NET formation in ARDS. In Respir Res on 2022 Jun 13 by Chao Song, Haitao Li,et al..PMID:35698192, , (2022),
PMID: 35698192
sRAGE Inhibits the Mucus Hypersecretion in a Mouse Model with Neutrophilic Asthma. In Immunol Invest on 2022 Jul by Xiaobo Zhang, Jun Xie,et al..PMID:34018452, , (2022),
PMID: 34018452
Neferine, a novel ROCK1-targeting inhibitor, blocks EMT process and induces apoptosis in non-small cell lung cancer. In J Cancer Res Clin Oncol on 2022 Aug 19 by Po Hu, Peng Wan, et al..PMID:35984492, , (2022),
PMID: 35984492
Resveratrol Protects Against Nicotine-Induced Apoptosis by Enhancing Autophagy in BEAS-2B Lung Epithelial Cells, , (2022),
PMID: #N/A
Canonical and noncanonical pyroptosis are both activated in periodontal inflammation and bone resorption. In J Periodontal Res on 2022 Dec by Rui Zhang, Zhiwu Wu, et al..PMID:36146901, , (2022),
PMID: 36146901
Combined Administration of Curcumin and Chondroitin Sulfate Alleviates Cartilage Injury and Inflammation via NF-κB Pathway in Knee Osteoarthritis Rats. In Front Pharmacol on 2022 May 19 by Ting Guan, Liu-Gang Ding, et al..PMID: 35662715, , (2022),
PMID: 35662715
Insoluble Fiber in Barley Leaf Attenuates Hyperuricemic Nephropathy by Modulating Gut Microbiota and Short-Chain Fatty Acids. In Foods on 2022 Nov 2 by Yongmei Li, Lu Li, et al..PMID:36360095, , (2022),
PMID: 36360095
Curcumin induces apoptosis and inhibits the growth of adrenocortical carcinoma: Identification of potential candidate genes and pathways by transcriptome analysis. In Oncol Lett on 2021 Jun by Xuemei Huang, Chunfeng Liang,et al..PMID:33907586, , (2021),
PMID: 33907586
sRAGE Inhibits the Mucus Hypersecretion in a Mouse Model with Neutrophilic Asthma. In Immunol Invest on 2021 May 21 by Xiaobo Zhang, Jun Xie,et al..PMID:34018452, , (2021),
PMID: 34018452
miR‑29a‑3p regulates the epithelial‑mesenchymal transition via the SPARC/ERK signaling pathway in human bronchial epithelial cells. In Int J Mol Med on 2021 Sep by Xiaobo Zhang, Jun Xie et al..PMID: 34278471, , (2021),
PMID: 34278471
Nicotinamide mononucleotide (NMN) protects bEnd.3 cells against H2O2-induced damage via NAMPT and the NF-κB p65 signalling pathway. In FEBS Open Bio on 2021 Mar by Xiujun Deng, Xinghuan Liang,et al..PMID:33340447, , (2021),
PMID: 33340447
Bioactive glass promotes the barrier functional behaviors of keratinocytes and improves the Re-epithelialization in wound healing in diabetic rats. In Bioact Mater on 2021 Mar 21 by Fengling Tang, Junliang Li, et al..PMID:33817423, , (2021),
PMID: 33817423
Alleviative Effect of Alpha-Lipoic Acid on Cognitive Impairment in High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats. In Front Aging Neurosci on 2021 Nov 12 by Chih-Yuan Ko, Jian-Hua Xu,et al..PMID:34867302, , (2021),
PMID: 34867302
MiR-221-3p-mediated downregulation of MDM2 reverses the paclitaxel resistance of non-small cell lung cancer in vitro and in vivo. In Eur J Pharmacol on 2021 May 15 by Liwei Ni, Jianhao Xu,et al..PMID:33771522, , (2021),
PMID: 33771522
miR-143/145 inhibits Th9 cell differentiation by targeting NFATc1. In Mol Immunol on 2021 Apr by Xin Qiu, Qiuyue Shi,et al..PMID:33446394, , (2021),
PMID: 33446394
Kuanxiong aerosol inhibits apoptosis and attenuates isoproterenol-induced myocardial injury through the mitogen-activated protein kinase pathway. In J Ethnopharmacol on 2021 Apr 6 by Yan Lu, Meiling Yang,et al..PMID:33359915, , (2021),
PMID: 33359915
Baicalein suppresses growth of non-small cell lung carcinoma by targeting MAP4K3. In Biomed Pharmacother on 2021 Jan by Jian Li, Lijun Yan,et al..PMID:33166766, , (2021),
PMID: 33166766
Deficiency of coiled-coil domain containing 80 increases plasma cholesterol by decreasing fecal sterols excretion in hypercholesterolemic mice. In J Nutr Biochem on 2021 Dec by Wenyun Li, Zhuo Sun,et al..PMID:34563664, , (2021),
PMID: 34563664
Expression of functional thyroid-stimulating hormone receptor in microglia. In Ann Endocrinol (Paris) on 2021 Dec 9 by Yuping Liu, Haiyan Yang,et al..PMID:34896340, , (2021),
PMID: 34896340
METTL3 Depletion Contributes to HR+/HER2- Breast Cancer Progression and Drug Resistance via m6A Modification of Constituents of the CDKN1A/EMT and BAX/caspase-9/-3/-8 Signalling Pathways, , (2021),
PMID:
1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways. In Eur J Med Chem on 2021 Nov 15 by Jiang-Jiang Tang, Min-Ran Wang, et al..PMID:34315042, , (2021),
PMID: 34315042
Tri-ortho-cresyl phosphate (TOCP)-induced reproductive toxicity involved in placental apoptosis, autophagy and oxidative stress in pregnant mice.In Environ Toxicol on 2020 Jan; by Yang B, Wang X, et al..PMID:31566301, , (2020),
PMID: 31566301
Phytoestrogens protect joints in collagen induced arthritis by increasing IgG glycosylation and reducing osteoclast activation.In Int Immunopharmacol on 2020 Mar 12 by Du N, Song L, et al..PMID:32172207, , (2020),
PMID: 32172207
Soluble advanced glycosylation receptor is apotential target for the treatment of neutrophilic asthma., , (2020),
PMID:
Nicotinamide mononucleotide (NMN) protects bEnd.3 cells against H2O2-induced damage via NAMPT and the NF-kB p65 signalling pathway. In FEBS Open Bio on 2021 Mar by Xiujun Deng, Xinghuan Liang, et al..PMID:33340447, , (2020),
PMID: 33340447
Glycogen Phosphorylase B Is Regulated by miR101-3p and Promotes Hepatocellular Carcinoma Tumorigenesis. In Front Cell Dev Biol on 2020 Nov 25 by Guangying Cui, Huifen Wang, et al..PMID:33324633, , (2020),
PMID: 33324633
Administration of low-dose resveratrol attenuated hepatic inflammation and lipid accumulation in high cholesterol-fructose diet-induced rat model of nonalcoholic fatty liver disease. In Chin J Physiol on Jul-Aug 2020 by Chih-Chun Chang, Chieh-Yu Chang,et al..PMID:32859881, , (2020),
PMID: 32859881
Possible Involvement of alpha B-crystallIn In the cardioprotective effect of n-butanol extract of Potentilla anserIna L. on myocardial ischemia/reperfusion Injury In rat. In PhytomedicIne on 2019 Mar 1 by Zhang L, Jian LL, et al.. PMID:30940361, , (2019),
PMID: 30940361
ThapsigargIn Induces apoptosis In adrenocortical carcInoma by activatIng endoplasmic reticulum stress and the JNK signalIng pathway: an In vitro and In vivo study. In Drug Des Devel Ther on 2019 Aug 12 by Wu L, Huang X, et al..PMID:31496655, , (2019),
PMID: 31496655
Tauroursodeoxycholic acid mediates endoplasmic reticulum stress and autophagy In adrenocortical carcInoma cells. In Oncol Lett. on 2019 Dec by Huang X, Wu L, et al..PMID:31814847, , (2019),
PMID: 31814847
Expression and secretion of neuregulin-1 in cardiac microvascular endothelial cells treated with angiogenic factors .In Exp Ther Med.On 2018 Apr by Wu C, Gui C et al..PMID:29545886, , (2018),
PMID: 29545886
Astragalus polysaccharides exerts anti-infective activity by inducing human cathelicidin antimicrobial peptide LL-37 in respiratory epithelial cells.In Phytother Res. On 2018 Aug by Zhao L, Tan S et al..PMID: 29672953, , (2018),
PMID: 29672953
Mansonone E from Mansonia gagei Inhibited α-MSH-Induced Melanogenesis in B16 Cells by Inhibiting CREB Expression and Phosphorylation in the PI3K/Akt Pathway,In Biol Pharm Bull.On 2018 by Nishina A, Miura A et al..PMID: 29709914, , (2018),
PMID: 29709914
Co-culture with TM4 cells enhances the proliferation and migration of rat adipose-derived mesenchymal stem cells with high stemness.In Cytotechnology.On 2018 Oct by Luo Y1, Mohsin A et al..PMID:30032334, , (2018),
PMID: 30032334
The inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus).In BMC Genomics. On 2018 Aug 23 by Wang S, Luo Z et al..PMID: 30139327, , (2018),
PMID: 30139327
Paclitaxel promotes lung cancer cell apoptosis via MEG3-P53 pathway activation.In Biochem Biophys Res Commun. On 2018 Sep 26 by Xu J, Su C et al..PMID:30173893, , (2018),
PMID: 30173893
Tanshinone IIA Attenuates Insulin Like Growth Factor 1 -Induced Cell Proliferation in PC12 Cells through the PI3K/Akt and MEK/ERK Pathways.In Int J Mol Sci. On 2018 Sep 12 by Wang H, Su X et al..PMID: 30213025, , (2018),
PMID: 30213025
miR?199b?5p inhibits triple negative breast cancer cell proliferation, migration and invasion by targeting DDR1.In Oncol Lett. On 2018 Oct by Wu A1, Chen Y et al..PMID:30250555, , (2018),
PMID: 30250555
Palmitic acid triggers cell apoptosis in RGC-5 retinal ganglion cells through the Akt/FoxO1 signaling pathway.In Metab Brain Dis on 2017 Apr by Panshi Yan, Shu Tang,et al..PMID: 27928692, , (2017),
PMID: 27928692
The atypical antipsychotic agent, clozapine, protects against corticosterone-induced death of PC12 cells by regulating the Akt/FoxO3a signaling pathway.In Mol Neurobiol on 2017 Jul by Zhiwen Zeng, Xue Wang,et al..PMID: 27173157, , (2017),
PMID: 27173157
The DEAD-Box RNA Helicase DDX3 Interacts With M 6 A RNA Demethylase ALKBH5.In Stem Cells Int on 2017 Nov 23 by Abdullah Shah, Farooq Rashid ,et al..PMID: 29333169, , (2017),
PMID: 29333169
Combined Effects of Starvation and Butyrate on Autophagy-Dependent Gingival Epithelial Cell Death.In J Periodontal Res on 2017 Jun by M Evans, T Murofushi,et al..PMID: 27624546, , (2017),
PMID: 27624546
LAMC1 mRNA Promotes Malignancy of Hepatocellular Carcinoma Cells by Competing for MicroRNA-124 Binding With CD151.In IUBMB Life on 2017 Aug by Zhan-Po Yang, Hong-Shun Ma,et al..PMID:28524360, , (2017),
PMID: 28524360
Propofol Postconditioning Attenuates Hippocampus Ischemia-Reperfusion Injury via Modulating JAK2/STAT3 Pathway in Rats After Autogenous Orthotropic Liver Transplantation.In Brain Res on 2017 Feb 15 by Lili Jia, Fei Wang,et al..PMID: 27998796, , (2017),
PMID: 27998796
Bruceine D induces apoptosis in human chronic myeloid leukemia K562 cells via mitochondrial pathway.In Am J Cancer Res on 2016 Mar 15 by Jian-Ye Zhang, Min-Ting Lin et al..PMID: 27186433, , (2016),
PMID: 27186433
MicroRNA-497 suppresses cell proliferation and induces apoptosis through targeting PBX3 in human multiple myeloma.In Am J Cancer Res on 2016 Dec 1 by Tianhua Yu , Xuanhe Zhang et al..PMID:28042507 , , (2016),
PMID: 28042507
Prostaglandin E2 promotes human cholangiocarcinoma cell proliferation, migration and invasion through the upregulation of β-catenin expression via EP3-4 receptor.In Oncol Rep on 2015 Aug Oct by Mingzhan Du, Feng Shi ,et al..PMID: 26058972, , (2016),
PMID: 26058972
Prostaglandin E2 promotes hepatocellular carcinoma cell invasion through upregulation of YB-1 protein expression.In Int J Oncol on 2014 Mar by Hai Zhang, Shanyu Cheng, et al..PMID: 24378923 , , (2016),
PMID: 24378923
Genistein upregulates LDLR levels via JNK-mediated activation of SREBP-2.In Food Nutr Res on 2016 May 20 by Medicia Kartawijaya, Hye Won Han et al..PMID: 27211318, , (2016),
PMID: 27211318
Blockade of Orai1 Store-Operated Calcium Entry Protects Against Renal Fibrosis .In J Am Soc Nephrol on 2016 Oct by Xiaoyi Mai, Jinyan Shang et al..PMID: 26940090 , , (2016),
PMID: 26940090
Liganded retinoic acid X receptor α represses connexin 43 through a potential retinoic acid response element in the promoter region.In Pediatr Res on 2016 Jul by Ruoyi Gu , Jun Xu et al..PMID:26991262, , (2016),
PMID: 26991262
PIK3C2A mRNA functions as a miR-124 sponge to facilitate CD151 expression and enhance malignancy of hepatocellular carcinoma cells.In Oncotarget on 2016 Jul 12 by Tao Liu , Cai-Hua Zu et al..PMID: 27270320, , (2016),
PMID: 27270320
MiRNA-29a as a tumor suppressor mediates PRIMA-1Met-induced anti-myeloma activity by targeting c-Myc. In Oncotarget on 2016 Feb 9 by Manujendra N Saha, Jahangir Abdi, et al..PMID: 26771839, , (2016),
PMID: 26771839
Fenofibrate suppressed proliferation and migration of human neuroblastoma cells via oxidative stress dependent of TXNIP upregulation.In Biochem Biophys Res Commun on 2015 May 15 by Cunjin Su, Aiming Shi et al..PMID:25839662, , (2015),
PMID: 25839662
Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways.In Psychopharmacology (Berl).On 2015 Dec 2 by Zhiwen Zeng, Haitao Wang et al..PMID: 26626328, , (2015),
PMID: 26626328
IGF-1 signaling via the PI3K/Akt pathway confers neuroprotection in human retinal pigment epithelial cells exposed to sodium nitroprusside insult.In Drug Des Devel Ther.On 2015 Sep 4 by Chunyang Du , Yonghong Shi et al..PMID:26379423 , , (2015),
PMID: 26379423
miR-137 and miR-197 induce apoptosis and suppress tumorigenicity by targeting MCL-1 in multiple myeloma.In Clin Cancer Res on 2015 May 15 by Yijun Yang , Fei Li et al..PMID:25724519 , , (2015),
PMID: 25724519
Combinational treatment of curcumin and quercetin against gastric cancer MGC-803 cells in vitro Molecules on 2015 Jun 22 by Jian-Ye Zhang , Min-Ting Lin et al..PMID:26111180 , , (2015),
PMID: 26111180
Nerve growth factor protects retinal ganglion cells against injury induced by retinal ischemia�Creperfusion in rats.In Growth Factors on 2015 Apr by Qian Chen , Haitao Wang et al..PMID: 25707536, , (2015),
PMID: 25707536
Transcription factor Nrf1 is negatively regulated by its O-GlcNAcylation status.In FEBS Lett on 2015 Aug 19 by Jiayu Chen, Xiping Liu et al..PMID: 26231763, , (2015),
PMID: 26231763
IL12p40 Regulates Functional Development of Human CD4+ T Cells Enlightenment by the Elevated Expressions of IL12p40 in Patients With Inflammatory Bowel Diseases.In Medicine (Baltimore) on 2015 Mar by Xiaobing Wang, Ting Wu et al..PMID:25761185, , (2015),
PMID: 25761185
PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus. In Nat Commun on 2015 Aug 27 by Daqian Xu, Zheng Wang,et al..PMID:26311497, , (2015),
PMID: 26311497
Fermentation of soy milk via Lactobacillus plantarum improves dysregulated lipid metabolism in rats on a high cholesterol diet.In PLoS One on 2014 Feb 10 by Yunhye Kim, Sun Yoon et al..PMID:24520358, , (2014),
PMID: 24520358
Increased striatal adenosine A2A receptor levels is an early event in Parkinson's disease-related pathology and it is potentially regulated by miR-34b. In Neurobiol Dis on 2014 Sep by Slvia Porta, Sandra P Buira,et al..PMID:24892887, , (2014),
PMID: 24892887
Differential apoptosis gene expressions of rhabdomyosarcoma cells in response to enterovirus 71 infection.In BMC Infect Dis on 2012 Nov 28 by Shi W, Li X,et al..PMID:23191987, , (2012),
PMID: 23191987
Cardamonin Protects Septic Mice From Acute Lung Injury by Preventing Endothelial Barrier Dysfunction.In J Biochem Mol Toxicol on 2012 Jul by Zhifeng Wei, Jian Yang,et al..PMID:22696397, , (2012),
PMID: 22696397
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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep