• Product NameKCNA5 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total KCNA5 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human KCNA5.
• Target NameKCNA5
• Alternative Names    Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel subunit Kv1.5; HK2; HPCN1;
• Accession No. Swiss-Prot: P22460
  NCBI Gene ID: 3741
• UniprotP22460
• Gene ID3741;
• SDS-PAGE MW 68kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. This channel displays rapid activation and slow inactivation. May play a role in regulating the secretion of insulin in normal pancreatic islets. Isoform 2 exhibits a voltage-dependent recovery from inactivation and an excessive cumulative inactivation.

Tamkun M.M., FASEB J. 5:331-337(1991).
Philipson L.H., Proc. Natl. Acad. Sci. U.S.A. 88:53-57(1991).
Curran M.E., Genomics 12:729-737(1992).

• Western blot analysis of extracts from 293 cells, using KCNA5 antibody #34915.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting