• Product NamePTPRZ1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total PTPRZ1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from N-terminal of human PTPRZ1.
• Target NamePTPRZ1
• Alternative Names    R-PTP-zeta; Protein-tyrosine phosphatase receptor type Z polypeptide 1;
• Accession No. Swiss-Prot: P23471
  NCBI Gene ID: 5803
• UniprotP23471
• Gene ID5803;
• SDS-PAGE MW 250kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades By similarity.

Krueger N.X., Proc. Natl. Acad. Sci. U.S.A. 89:7417-7421(1992).
Levy J.B., J. Biol. Chem. 268:10573-10581(1993).
Hillier L.W., Nature 424:157-164(2003).

• Western blot analysis of extracts from A549 cells, using PTPRZ1 antibody #34977.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting