• Product NameSEPT7 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SEPT7 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human SEPT7.
• Target NameSEPT7
• Alternative Names    CDC10; SEP7; septin 7;
• Accession No. Swiss-Prot: Q16181
  NCBI Gene ID: 989
• UniprotQ16181
• Gene ID989;
• SDS-PAGE MW 48kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000

Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.

Nakatsuru S., Biochem. Biophys. Res. Commun. 202:82-87(1994).
Rush J., Nat. Biotechnol. 23:94-101(2005).
Olsen J.V., Cell 127:635-648(2006).

• Western blot analysis of extracts from MCF-7 cell, HuvEc cells and HeLa cells, using SEPT7 antibody #35016.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting