• Product NameSCN9A Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total SCN9A protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human SCN9A.
• Target NameSCN9A
• Alternative Names    Sodium channel protein type 9 subunit alpha; Sodium channel protein type IX subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.7; Neuroendocrine sodium channel; hNE-Na
• Accession No. Swiss-Prot: Q15858
  NCBI Gene ID: 6335
• UniprotQ15858
• Gene ID6335;
• SDS-PAGE MW 220kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:2000
  Immunohistochemistry: 1:100 - 1:300

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na+ channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain By similarity.

Klugbauer N., EMBO J. 14:1084-1090(1995).
Cox J.J., Nature 444:894-898(2006).
Raymond C.K., J. Biol. Chem. 279:46234-46241(2004).

• Western blot analysis of extracts from RAW cells, using SCN9A antiobdy #35056.
• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using SCN9A antibody #35056.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting