• Product NameITGB6 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ITGB6 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from internal residues of human integrin, beta 6
• Target NameITGB6
• Alternative Names    ITGB6;ITB6;beta 6; integrin
• Accession No. Swiss-Prot#: P18564
  NCBI Gene ID: 3694
  Gene Accssion: BC121178
• UniprotP18564
• Gene ID3694;
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. Integrin, beta 6 has been shown to interact with FHL2. Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.

• The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ITGB6 Antibody at dilution 1/70, on the right is treated with fusion protein. (Original magnification: ×200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting