• Product NameIRAK4 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total IRAK4 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from internal residues of human interleukin-1 receptor-associated kinase 4
• Target NameIRAK4
• Alternative Names    IPD1; REN64; IRAK-4; NY-REN-64
• Accession No. Swiss-Prot#: Q9NWZ3
  NCBI Gene ID: 51135
  Gene Accssion: BC013316
• UniprotQ9NWZ3
• Gene ID51135;
• Concentration 1.7mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #35788 at dilution 1/40.
• Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #35788 at dilution 1/40.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting