• Product NameACMSD Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total ACMSD protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFull length fusion protein
• Target NameACMSD
• Alternative Names    Picolinate carboxylase;aminocarboxymuconate semialdehyde decarboxylase
• Accession No. Swiss-Prot#: Q8TDX5
  NCBI Gene ID: 130013
  Gene Accssion: BC016018
• UniprotQ8TDX5
• Gene ID130013;
• SDS-PAGE MW 38kd
• Concentration 0.8mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

• Gel: 10%SDS-PAGE
  Lysate: 40ug Raji cell
  Primary antibody: 1/400 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 20 seconds

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting