• Product NameAMBRA1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total AMBRA1 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from internal residues of human autophagy/beclin-1 regulator 1
• Target NameAMBRA1
• Alternative Names    DCAF3; WDR94
• Accession No. Swiss-Prot#: Q9C0C7
  NCBI Gene ID: 55626
  Gene Accssion: BC045609
• UniprotQ9C0C7
• Gene ID55626;
• Concentration 1.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

Human AMBRA1, which encodes a deduced 1,269-amino acid protein. Ambra1 was expressed throughout development in mice, with strong staining in the neuroepithelium. Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.

• Immunohistochemical analysis of paraffin-embedded Human brain tissue using #36091 at dilution 1/50.
• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #36091 at dilution 1/50.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting