• Product NameMYLK3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total MYLK3 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to residues near the N terminal of human myosin light chain kinase 3
• Target NameMYLK3
• Alternative Names    MLCK; MLCK2; caMLCK
• Accession No. Swiss-Prot#: Q32MK0
  NCBI Gene ID: 91807
  Gene Accssion: BC109097
• UniprotQ32MK0
• Gene ID91807;
• Concentration 2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

YLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.

• Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #36204 at dilution 1/30.
• Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using #36204 at dilution 1/30.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting