• Product NameABI3BP Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ABI3BP protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from internal residues of human ABI family, member 3 (NESH) binding protein
• Target NameABI3BP
• Alternative Names    TARSH; NESHBP
• Accession No. Swiss-Prot#: Q7Z7G0
  NCBI Gene ID: 25890
  Gene Accssion: BC030221
• UniprotQ7Z7G0
• Gene ID25890;
• Concentration 2.4mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.

• Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using #36249 at dilution 1/60.
• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #36249 at dilution 1/60.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting