• Product NameKLRB1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB,IHC,ELISA
• Species ReactivityHuman, Mouse
• SpecificityThe antibody detects endogenous levels of total KLRB1 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from internal residues of human killer cell lectin-like receptor subfamily B, member 1
• Target NameKLRB1
• Alternative Names    NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A
• Accession No. Swiss-Prot#: Q12918
  NCBI Gene ID: 3820
  Gene Accssion: BC114516
• UniprotQ12918
• Gene ID3820;
• SDS-PAGE MW 25kd
• Concentration 1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  Immunohistochemistry: 1:50-1:200

Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus.

• Gel: 8%SDS-PAGE, Lysate: 40ug, Lane 1-2: Human fetal intestines tissue and Human fetal liver tissue lysates, Primary antibody: 36323(KLRB1 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 seconds
• Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #36323.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting