• Product NamePABPC1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total PABPC1 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from internal residues of human poly(A) binding protein, cytoplasmic 1
• Target NamePABPC1
• Alternative Names    PAB1; PABP; PABP1; PABPC2; PABPL1
• Accession No. Swiss-Prot#: P11940
  NCBI Gene ID: 26986
  Gene Accssion: BC015958
• UniprotP11940
• Gene ID26986;
• SDS-PAGE MW 71kd
• Concentration 2.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

• Gel: 8%SDS-PAGE
  Lysates (from left to right): LoVo and Hela cell
  Amount of lysate: 40ug per lane
  Primary antibody: 1/500 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 3 seconds

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting