• Product NamePHLPP1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total PHLPP1 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to residues near the C terminal of human PH domain and leucine rich repeat protein phosphatase 1
• Target NamePHLPP1
• Alternative Names    PHLPP1
• Accession No. Swiss-Prot#: O60346
  NCBI Gene ID: 23239
  Gene Accssion: BC014927/O60346
• UniprotO60346
• Gene ID23239;
• Concentration 2.1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

• Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #36693 at dilution 1/35.
• Immunohistochemical analysis of paraffin-embedded Human brain tissue using #36693 at dilution 1/35.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting