Product Detail
Product NameATP1A1 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
Immunogen DescA synthetic peptide of human Na+/K+-ATPase (NP_000692.2).
ConjugateUnconjugated
Other NamesATP1A1;ATPase Na+/K+ transporting subunit alpha 1;ATP1A;CMT2DD;HOMGSMR2
Accession NoUniprot:P05023
GeneID:476
Uniprot
P05023
Gene ID
476
Calculated MW74kDa/109kDa/112kDa/113kDa
Sdspage MW100KDa
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Na+/K+-ATPase antibody.
Immunohistochemistry of paraffin-embedded human lung cancer using Na+/K+-ATPase Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse kidney using Na+/K+-ATPase Rabbit pAb.
Immunohistochemistry of paraffin-embedded human liver cancer using Na+/K+-ATPase Rabbit pAb.
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
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