• Product NameCDC37 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CDC37 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human cell division cycle 37 homolog (S. cerevisiae)
• Target NameCDC37
• Alternative Names    P50CDC37
• Accession No. Swiss-Prot#: Q16543
  NCBI Gene ID: 11140
  Gene Accssion: NP_008996.1
• UniprotQ16543
• Gene ID11140;
• SDS-PAGE MW 44kd
• Concentration 0.7mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:15-1:50

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

• Gel: 10%SDS-PAGE
  Lysate: 40ug Hela cell
  Primary antibody: 1/100 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 90 seconds
• Immunohistochemical analysis of paraffin-embedded Human brain tissue using #36786 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting