• Product NameGJC2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total GJC2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human gap junction protein, gamma 2, 47kDa
• Target NameGJC2
• Alternative Names    Cx47; HLD2; GJA12; SPG44; CX46.6; LMPH1C; PMLDAR
• Accession No. Swiss-Prot#: Q5T442
  NCBI Gene ID: 57165
  Gene Accssion: NP_065168
• UniprotQ5T442
• Gene ID57165;
• SDS-PAGE MW 47kd
• Concentration 2.1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  

This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.

• Gel: 10%SDS-PAGE
  Lysate: 30ug OP9 cell
  Primary antibody: 1/450 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 30 seconds

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting