• Product NameFAT3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total FAT3 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human FAT tumor suppressor homolog 3 (Drosophila)
• Target NameFAT3
• Alternative Names    CDHF15; CDHR10
• Accession No. Swiss-Prot#: Q8TDW7
  NCBI Gene ID: 120114
  Gene Accssion: NP_001008781
• UniprotQ8TDW7
• Gene ID120114;
• Concentration 0.7mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). The atypical cadherin Fat3 ensures that retinal amacrine cells (ACs) develop this unipolar morphology. Fat3 expression was restricted to the nervous system, for example in the brain, it is expressed in a variety of regions and axon fascicles. However, its strongest expression was observed in the olfactory bulb and retina.

• Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37294 at dilution 1/20.
• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #37294 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting