• Product NameAKT2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total AKT2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human v-akt murine thymoma viral oncogene homolog 2
• Target NameAKT2
• Alternative Names    PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA
• Accession No. Swiss-Prot#: P31751
  NCBI Gene ID: 208
  Gene Accssion: NP_001617
• UniprotP31751
• Gene ID208;
• Concentration 2.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

• Immunohistochemical analysis of paraffin-embedded Human brain tissue using #37320 at dilution 1/70.
• Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #37320 at dilution 1/70.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting