• Product NameNEK10 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total NEK10 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human NIMA-related kinase 10
• Target NameNEK10
• Alternative Names    FLJ32685; NEK10; Never in mitosis A-related kinase 10;
• Accession No. Swiss-Prot#: Q6ZWH5
  NCBI Gene ID: 152110
  Gene Accssion: NP_955379
• UniprotQ6ZWH5
• Gene ID152110;
• Concentration 0.7mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

Nek10 (NIMA (never in mitosis gene a)-related kinase 10) is a 712 amino acid protein belonging to the NIMA subfamily of kinases and functions as a magnesium-dependent serine/threonine protein kinase. Kinases of the NIMA subfamily are typically involved in genotoxic stress response and DNA replication. Nek10 is expressed in brain and may contain a 14-3-3 interaction motif in its C-terminus. The gene encoding Nek10 has been localized to a region on chromosome 3 that may contribute to vulnerability to addictions. Due to alternative splicing events, three isoforms exist for Nek10.

• Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37381 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting