• Product NameJAG1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total JAG1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human jagged 1
• Target NameJAG1
• Alternative Names    AGS; AHD; AWS; HJ1; CD339; JAGL1
• Accession No. Swiss-Prot#: P78504
  NCBI Gene ID: 182
  Gene Accssion: NP_000205/P78504
• UniprotP78504
• Gene ID182;
• Concentration 1.5mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

• Immunohistochemical analysis of paraffin-embedded Human brain tissue using #37668 at dilution 1/20.
• Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #37668 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting