• Product NameARHGEF12 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ARHGEF12 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human Rho guanine nucleotide exchange factor (GEF) 12
• Target NameARHGEF12
• Alternative Names    LARG; PRO2792
• Accession No. Swiss-Prot#: Q9NZN5
  NCBI Gene ID: 23365
  Gene Accssion: NP_056128
• UniprotQ9NZN5
• Gene ID23365;
• Concentration 1.2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.

• Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using #37694 at dilution 1/20.
• Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #37694 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting