• Product NameMRGPRX1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total MRGPRX1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human MAS-related GPR, member X1
• Target NameMRGPRX1
• Alternative Names    GPCR; MGRG2; MRGX1; SNSR4
• Accession No. Swiss-Prot#: Q96LB2
  NCBI Gene ID: 259249
  Gene Accssion: NP_671732
• UniprotQ96LB2
• Gene ID259249;
• Concentration 0.7mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.

• Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37739 at dilution 1/20.
• Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37739 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting