• Product NamePPARGC1A Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total PPARGC1A protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
• Target NamePPARGC1A
• Alternative Names    LEM6; PGC1; PGC1A; PGC-1v; PPARGC1; PGC-1(alpha)
• Accession No. Swiss-Prot#: Q9UBK2
  NCBI Gene ID: 10891
  Gene Accssion: NP_037393/Q9UBK2
• UniprotQ9UBK2
• Gene ID10891;
• SDS-PAGE MW 91kd
• Concentration 0.8 mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination.?

• Gel: 8%SDS-PAGE
  Lysates (from left to right): Human fetal muscle tissue
  Amount of lysate: 40ug per lane
  Primary antibody: 1/300 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 2 minutes

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting