• Product NamePON1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHuman, Mouse, Rat
• SpecificityThe antibody detects endogenous levels of total PON1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide of human PON1
• Target NamePON1
• Alternative Names    ESA; PON; MVCD5
• Accession No. Swiss-Prot#: P27169
  NCBI Gene ID: 5444
  Gene Accssion: NP_000437/P27169
• UniprotP27169
• Gene ID5444;
• SDS-PAGE MW 40kd
• Concentration 0.5 mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:1000-1:5000
  Immunohistochemistry: 1:50-1:200

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.

• Gel: 8%SDS-PAGE
  Lysates (from left to right): Hela, skov3 and A549 cell, mouse liver and human ovarian cancer tissue
  Amount of lysate: 40ug per lane
  Primary antibody: 1/500 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 20 seconds
• Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using #37840 at dilution 1/40.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting