• Product NameCDKN1C antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total CDKN1C protein.
• Immunogen TypePeptide
• Immunogen DescriptionA synthetic peptide of human CDKN1C/p57 Kip2 (NP_000067.1).
• Target NameCDKN1C
• Alternative Names    CDKN1C;BWCR;BWS;KIP2;WBS;p57;p57Kip2
• Accession No. Uniprot:P49918
  GeneID:1028
• UniprotP49918
• Gene ID1028
• SDS-PAGE MW 57KDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

• Western blot analysis of extracts of various cell lines, using CDKN1C/p57 Kip2 antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting