• Product NameITGB3 antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total ITGB3 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human ITGB3.
• Target NameITGB3
• Alternative Names    GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16;
• Accession No. Swiss-Prot#: P05106
  NCBI Gene ID: 3690
• UniprotP05106
• Gene ID3690;
• SDS-PAGE MW 87kd
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

• Western blot analysis of extracts of various cell lines, using ITGB3 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting