• Product NameDISC1 antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total DISC1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionRecombinant fusion protein of human DISC1 (NP_001158009.1).
• Target NameDISC1
• Alternative Names    DISC1;C1orf136;SCZD9
• Accession No. Uniprot:Q9NRI5
  GeneID:27185
• UniprotQ9NRI5
• Gene ID27185
• SDS-PAGE MW 105kDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000

This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• Western blot analysis of extracts of various cell lines, using DISC1 antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting