• Product NameCLDN2 antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB IF
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total CLDN2 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human CLDN2.
• Target NameCLDN2
• Accession No. Swiss-Prot#: P57739
  NCBI Gene ID: 9075
• UniprotP57739
• Gene ID9075;
• SDS-PAGE MW 24kd
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:2000
  Immunofluorescence: 1:50 - 1:100
  

This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.

• Immunofluorescence analysis of HeLa cell using CLDN2 antibody. Blue: DAPI for nuclear staining.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting