• Product NameCPSF3L antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB,IF
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total CPSF3L protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human CPSF3L.
• Target NameCPSF3L
• Alternative Names    RC68; INT11; RC-68; INTS11; CPSF73L;
• Accession No. Swiss-Prot#: Q5TA45
  NCBI Gene ID: 54973
• UniprotQ5TA45
• Gene ID54973;
• SDS-PAGE MW 67kd
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IF 1:10 - 1:100

The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005

• Western blot analysis of extracts of various cell lines, using CPSF3L at 1:1000 dilution.
• Immunofluorescence analysis of HeLa cells using CPSF3L . Blue: DAPI for nuclear staining.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting