• Product NameSMPD1 antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IF
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total SMPD1 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant fusion protein of human SMPD1 / ASM (NP_000534.3).
• Target NameSMPD1
• Alternative Names    SMPD1;ASM;ASMASE;NPD;SMPD1/ASM
• Accession No. Uniprot:P17405
  GeneID:6609
• UniprotP17405
• Gene ID6609
• SDS-PAGE MW 60kDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IF 1:10 - 1:100

The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.

• Western blot analysis of extracts of various cell lines, using SMPD1 / ASM antibody.
• Immunofluorescence analysis of HeLa cells using SMPD1 / ASM antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting